About Angelman Syndrome

Angelman Syndrome (AS) is a rare neurogenetic disorder caused by the absence of certain genes normally present on the copy of chromosome 15 inherited from the mother that affects approximately one in 15,000 people – about 500,000 individuals worldwide.

The Effects of Angelman Syndrome

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Mobility

Children and adults with AS typically have balance issues and motor impairment which cause some individuals to never be able to walk. Many individuals get around by wheel chair or crawling.

Resource - www.cureangelman.org
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Neurological

Epilepsy is common in individuals with Angelman Syndrome. Approximately 85% of individuals with Angelman Syndrome will experience seizures within the first three years of their life, although seizures in AS can present at any age. The good news is that there are multiple, effective treatment options for managing seizures.

Resource - www.cureangelman.org
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Developmental

Typical characteristics of AS are not usually evident at birth. Individuals with this disorder may have feeding difficulties as infants and noticeable delayed development around 6-12 months of age. They need intensive therapies to help develop functional skills.

Resource - www.cureangelman.org