{"id":9,"date":"2025-01-26T00:38:18","date_gmt":"2025-01-26T00:38:18","guid":{"rendered":"http:\/\/alwayshavingfunfoundation.org\/?page_id=9"},"modified":"2025-03-14T08:30:03","modified_gmt":"2025-03-14T15:30:03","slug":"about-angelman-syndrome","status":"publish","type":"page","link":"https:\/\/alwayshavingfunfoundation.org\/?page_id=9","title":{"rendered":"About Angelman Syndrome"},"content":{"rendered":"\n<p class=\"has-custom-color-1-color has-text-color has-link-color wp-elements-027b7f4f32e3c4f72f99458b9cb04a83 wp-block-paragraph\">Angelman Syndrome (AS) is a rare neurogenetic disorder caused by the absence of certain genes normally present on the copy of chromosome 15 inherited from the mother that affects approximately one in 15,000 people \u2013 about 500,000 individuals worldwide.<\/p>\n\n\n\n<p class=\"has-text-align-center has-custom-color-1-color has-text-color has-link-color has-large-font-size wp-elements-83178bdf731288c27ce66ab3c12f3206 wp-block-paragraph\"><strong>The Effects of Angelman Syndrome<\/strong><\/p>\n\n\n\n<p class=\"has-custom-color-1-color has-text-color has-link-color wp-elements-7f84c3509a401da98a34302d205dcce5 wp-block-paragraph\"><strong>Mobility<\/strong><br>Children and adults with AS typically have balance issues and motor impairment which cause some individuals to never be able to walk. Many individuals get around by wheel chair or crawling.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"768\" src=\"http:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_01-1024x768.jpg\" alt=\"\" class=\"wp-image-50\" srcset=\"https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_01-1024x768.jpg 1024w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_01-300x225.jpg 300w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_01-768x576.jpg 768w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_01-1536x1152.jpg 1536w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_01-2048x1536.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"has-custom-color-1-color has-text-color has-link-color wp-elements-e97b6b8e8fef281753dc1319da2653b9 wp-block-paragraph\"><strong>Neurological<\/strong><br>Epilepsy is common in individuals with Angelman Syndrome. Approximately 85% of individuals with Angelman Syndrome will experience seizures within the first three years of their life, although seizures in AS can present at any age. The good news is that there are multiple, effective treatment options for managing seizures.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"769\" src=\"http:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_02-1024x769.jpg\" alt=\"\" class=\"wp-image-49\" srcset=\"https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_02-1024x769.jpg 1024w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_02-300x225.jpg 300w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_02-768x577.jpg 768w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_02.jpg 1500w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"has-custom-color-1-color has-text-color has-link-color wp-elements-84d41a1dc0f2a535aa8cf73b013d6d2b wp-block-paragraph\"><strong>Developmental<\/strong><br>Typical characteristics of AS are not usually evident at birth. Individuals with this disorder may have feeding difficulties as infants and noticeable delayed development around 6-12 months of age. They need intensive therapies to help develop functional skills.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"769\" src=\"http:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_03-1024x769.jpg\" alt=\"\" class=\"wp-image-52\" srcset=\"https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_03-1024x769.jpg 1024w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_03-300x225.jpg 300w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_03-768x577.jpg 768w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_03.jpg 1500w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-ee856660 wp-block-buttons-is-layout-flex\"><\/div>\n\n\n\n<p class=\"has-custom-color-1-color has-text-color has-link-color wp-elements-aa574f3944db9b9806cf98486cc8fdd2 wp-block-paragraph\">*<sub>Foundation for Angelman Syndrome Therapeutics &#8211; <a href=\"https:\/\/cureangelman.org\/\">https:\/\/cureangelman.org\/<\/a><\/sub><\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Angelman Syndrome (AS) is a rare neurogenetic disorder caused by the absence of certain genes normally present on the copy of chromosome 15 inherited from the mother that affects approximately one in 15,000 people \u2013 about 500,000 individuals worldwide. The Effects of Angelman Syndrome MobilityChildren and adults with AS typically have balance issues and motor [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-9","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9"}],"version-history":[{"count":5,"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=\/wp\/v2\/pages\/9\/revisions"}],"predecessor-version":[{"id":102,"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=\/wp\/v2\/pages\/9\/revisions\/102"}],"wp:attachment":[{"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}