{"id":9,"date":"2025-01-26T00:38:18","date_gmt":"2025-01-26T00:38:18","guid":{"rendered":"http:\/\/alwayshavingfunfoundation.org\/?page_id=9"},"modified":"2025-03-14T08:30:03","modified_gmt":"2025-03-14T15:30:03","slug":"about-angelman-syndrome","status":"publish","type":"page","link":"https:\/\/alwayshavingfunfoundation.org\/?page_id=9","title":{"rendered":"About Angelman Syndrome"},"content":{"rendered":"\n<p class=\"has-custom-color-1-color has-text-color has-link-color wp-elements-027b7f4f32e3c4f72f99458b9cb04a83\">Angelman Syndrome (AS) is a rare neurogenetic disorder caused by the absence of certain genes normally present on the copy of chromosome 15 inherited from the mother that affects approximately one in 15,000 people \u2013 about 500,000 individuals worldwide.<\/p>\n\n\n\n<p class=\"has-text-align-center has-custom-color-1-color has-text-color has-link-color has-large-font-size wp-elements-83178bdf731288c27ce66ab3c12f3206\"><strong>The Effects of Angelman Syndrome<\/strong><\/p>\n\n\n\n<p class=\"has-custom-color-1-color has-text-color has-link-color wp-elements-7f84c3509a401da98a34302d205dcce5\"><strong>Mobility<\/strong><br>Children and adults with AS typically have balance issues and motor impairment which cause some individuals to never be able to walk. Many individuals get around by wheel chair or crawling.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"768\" src=\"http:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_01-1024x768.jpg\" alt=\"\" class=\"wp-image-50\" srcset=\"https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_01-1024x768.jpg 1024w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_01-300x225.jpg 300w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_01-768x576.jpg 768w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_01-1536x1152.jpg 1536w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_01-2048x1536.jpg 2048w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"has-custom-color-1-color has-text-color has-link-color wp-elements-e97b6b8e8fef281753dc1319da2653b9\"><strong>Neurological<\/strong><br>Epilepsy is common in individuals with Angelman Syndrome. Approximately 85% of individuals with Angelman Syndrome will experience seizures within the first three years of their life, although seizures in AS can present at any age. The good news is that there are multiple, effective treatment options for managing seizures.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"769\" src=\"http:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_02-1024x769.jpg\" alt=\"\" class=\"wp-image-49\" srcset=\"https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_02-1024x769.jpg 1024w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_02-300x225.jpg 300w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_02-768x577.jpg 768w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_02.jpg 1500w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<p class=\"has-custom-color-1-color has-text-color has-link-color wp-elements-84d41a1dc0f2a535aa8cf73b013d6d2b\"><strong>Developmental<\/strong><br>Typical characteristics of AS are not usually evident at birth. Individuals with this disorder may have feeding difficulties as infants and noticeable delayed development around 6-12 months of age. They need intensive therapies to help develop functional skills.<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"1024\" height=\"769\" src=\"http:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_03-1024x769.jpg\" alt=\"\" class=\"wp-image-52\" srcset=\"https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_03-1024x769.jpg 1024w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_03-300x225.jpg 300w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_03-768x577.jpg 768w, https:\/\/alwayshavingfunfoundation.org\/wp-content\/uploads\/2025\/02\/Chase_03.jpg 1500w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/figure>\n\n\n\n<div class=\"wp-block-buttons is-content-justification-center is-layout-flex wp-container-core-buttons-is-layout-a89b3969 wp-block-buttons-is-layout-flex\"><\/div>\n\n\n\n<p class=\"has-custom-color-1-color has-text-color has-link-color wp-elements-aa574f3944db9b9806cf98486cc8fdd2\">*<sub>Foundation for Angelman Syndrome Therapeutics &#8211; <a href=\"https:\/\/cureangelman.org\/\">https:\/\/cureangelman.org\/<\/a><\/sub><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Angelman Syndrome (AS) is a rare neurogenetic disorder caused by the absence of certain genes normally present on the copy of chromosome 15 inherited from the mother that affects approximately one in 15,000 people \u2013 about 500,000 individuals worldwide. The Effects of Angelman Syndrome MobilityChildren and adults with AS typically have balance issues and motor [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-9","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=\/wp\/v2\/pages\/9","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=9"}],"version-history":[{"count":5,"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=\/wp\/v2\/pages\/9\/revisions"}],"predecessor-version":[{"id":102,"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=\/wp\/v2\/pages\/9\/revisions\/102"}],"wp:attachment":[{"href":"https:\/\/alwayshavingfunfoundation.org\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=9"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}